Strain-dependent variation in Mycobacterium bovis BCG-induced human T-cell activation and gamma interferon production in vitro.

نویسندگان

  • Ana M Aguirre-Blanco
  • Pauline T Lukey
  • Jacqueline M Cliff
  • Hazel M Dockrell
چکیده

Three commonly used Mycobacterium bovis BCG vaccine strains elicited different magnitudes of T-cell activation and gamma interferon production in vitro in healthy BCG-vaccinated individuals. Glaxo 1077 exhibited the greatest stimulatory capacity, followed by Pasteur 1173 and then Danish 1331. These differences may affect in vitro stimulation and vaccination-induced immunogenicity.

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عنوان ژورنال:
  • Infection and immunity

دوره 75 6  شماره 

صفحات  -

تاریخ انتشار 2007